Ligation is the joining of two nucleotides, or two nucleic acid fragments, into a single polymeric chain through the action of an enzyme known as a ligase.

Ligation of DNA is a critical step in many modern molecular biology workflows. The sealing of nicks between adjacent residues of a single-strand break on a double-strand substrate and the …

Aug 25, 2025 · Ligation refers to the fundamental process of binding, tying, or joining distinct components together. This concept applies across various scientific and medical disciplines. It …

Share Kids Definition ligation noun li· ga· tion lī-ˈgā-shən : the act of tying a bodily part (as a blood vessel) with a ligature

LIGATION definition: 1. the act of tying a blood vessel or other tube in the body with a piece of thread or wire: 2…. Learn more.

Ligation is one of the crucial steps in gene cloning because the DNA ligase enzyme joins a DNA vector with the target gene sequence through their blunt or sticky ends.

The principle of ligation is attributed to Hippocrates and Galen. [1][2] In ancient Rome, ligatures were used to treat hemorrhoids. [3] Spanish Muslim doctor Al-Zahrawi described the …

Prison rules make the procedure, known as tubal ligation, available to inmates as part of regular obstetrical care.

Jan 24, 2024 · Tubal ligation is a surgery that involves making one or more small cuts in the lower stomach area, also called lower abdomen. The procedure uses medicine that keeps you from …

LIGATION definition: the act of ligating, especially of surgically tying up a bleeding artery. See examples of ligation used in a sentence.