BRCA Gene Changes: Cancer Risk and Genetic Testing
A fact sheet about the BRCA1 and BRCA2 genes, what to do if a person tests positive for alterations in one of these genes, and consequences of genetic testing.
BRCA1 and BRCA2 (PDQ®) - NCI - National Cancer Institute
Evidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer. This summary also contains information about the cancer risks associated with …
MRI, Surgery Reduce Cancer Deaths in Women with BRCA Changes
Apr 15, 2024 · For women with inherited harmful changes in BRCA genes, MRI surveillance and salpingo-oophorectomy can modestly reduce their risk of dying from breast and ovarian cancer, …
Genetic Testing Fact Sheet - NCI - National Cancer Institute
A fact sheet about genetic testing for inherited cancer risk. Includes who should consider testing, and how to understand test results.
Discovery – BRCA Connection to Breast and Ovarian Cancer
NCI-funded research helped identify inherited BRCA1 and BRCA2 genetic mutations and their connection to breast and ovarian cancer. From this research, a screening test was also developed to …
Surgery to Reduce the Risk of Breast Cancer
Dec 2, 2025 · A fact sheet that describes mastectomy and salpingo-oophorectomy, two surgeries that may be used to reduce the risks of breast and ovarian cancers in people, and nonsurgical options.
Hoja informativa sobre los cambios en el gen BRCA y las pruebas …
Hoja informativa sobre los genes BRCA1 y BRCA2, qué hacer si la prueba de una persona indica que tiene cambios en uno de estos genes y las consecuencias de las pruebas genéticas.
PALB2 and Associated Cancer Risks (PDQ®) - NCI
Feb 14, 2025 · Evidence-based, expert-reviewed summary about the PALB2 gene, the cancer risks associated with PALB2, screening, risk-reduction, treatment, and prognosis.
Olaparib Approved for Breast Cancers with BRCA Gene Mutations
Jan 29, 2018 · The Food and Drug Administration has approved olaparib (Lynparza®) to treat metastatic breast cancers that have inherited mutations in the BRCA1 or BRCA2 genes as well as a companion …
Cancer Risk for Women Carrying BRCA Mutations - NCI
Jul 12, 2017 · A Cancer Currents blog post on a large, prospective study of breast, ovarian, and contralateral breast cancer risks associated with BRCA1 and BRCA2 gene mutations.