The San Francisco 49ers have seen changes in their injury list as some key players return while others remain sidelined.

Isaac Guerendo and Renardo Green stood out during San Francisco 49ers practice Tuesday as they returned from their respective injuries.

Mac Jones will be sidelined for the remainder of the week and for the San Francisco 49ers ’ preseason finale against the Los Angeles Chargers on Saturday. 49ers coach Kyle Shanahan told reporters that Jones suffered a knee sprain and will be unavailable this week due to a knee sprain the quarterback suffered against the Las Vegas Raiders.

This is a significant blow to the 49ers' RB room since Taylor had secured a spot as a reliable third or fourth option who contributed on special teams. He posted a career-high 109 yards on 17 carries in San Francisco's Week 18 loss to the Arizona Cardinals last season.

The San Francisco 49ers are bringing back a familiar face under center. According to the Athletic's Matt Barrows, the 49ers are signing quarterback Nate Sudfeld after Sudfeld threw in a wide receiver workout Monday.

The San Francisco 49ers could cut ties with wide receiver Brandon Aiyuk depending on his performance following his return during the 2025 season.

San Francisco 49ers cornerback Chase Lucas has consistently made plays in training camp and preseason. He explained why after the win over Las Vegas.

It still feels like a fever dream or a practical joke, but Tom Brady is actually a part-owner of the Las Vegas Raiders. Brady is from Northern California and grew up a fan of the San Francisco 49ers.