A relatively comfortable victory is expected for the San Francisco 49ers (5-4) when they meet the Seattle Seahawks (4-5) on ...

The Seattle Seahawks (4-5) are 6.5-point underdogs in a road NFC West matchup with the San Francisco 49ers (5-4) on Sunday, ...

Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...

This week's DFS slate features a tilt between the 49ers and the Seahawks. The top DFS options from these two squads can be ...

What to look for from the top 49ers and Seahawks players and how to watch the game as they face off on Sunday, week 11.

Also, how Steve Spagnuolo's defense locked down a win for the Chiefs and the Ravens' inability to stop Ja'Marr Chase.

NFL Week 11 odds, picks, predictions, TV and streaming information for the Sunday football game between the Seattle Seahawks ...

A good illustrator of just how important their Week 10 win was comes via the USA TODAY NFL power rankings. San Francisco ...

The 49ers won a game this past Sunday, but they didn't improve. They played down to the Buccaneers, who have the worst ...

SportsLine's model simulated Tampa Bay Bucs vs. San Francisco 49ers 10,000 times and made its Week 10 NFL picks, predictions ...

The San Francisco 49ers squeaked out a win against the Tampa Bay Buccaneers and will now host the Seattle Seahawks in an NFC ...

On second-and-5 from the San Francisco 46-yard line, Brock Purdy looked to Pearsall on a pass over the middle of the field.