The San Francisco 49ers have seen changes in their injury list as some key players return while others remain sidelined.

Kyle Shanahan hopes nothing but the best for former San Francisco quarterback Trey Lance ahead of his return to Levi's Stadium on Saturday.

San Francisco coach Kyle Shanahan discussed the NFL's new rules around smelling salts after 49ers' training camp practice on Tuesday in Santa Clara.

With Mac Jones nursing a knee injury, the 49ers are adding a familiar face to their roster. Read PFR for more.

Nik Bonitto is in line for a massive payday. The superstar pass rusher is due for an extension, and the Denver Broncos want to do everything they can to keep a cornerstone on their defense around for ...

The 49ers have been searching for a quality third-string quarterback all offseason. That's why they're reuniting with Nate Sudfeld.

As the 2025 NFL season approaches, the San Francisco 49ers face concerns over depth in their backfield. Christian McCaffrey ...

The 49ers may target Commanders RB Brian Robinson Jr. to add depth behind Christian McCaffrey and strengthen Shanahan’s offense.

As the San Francisco 49ers close out the 2025 preseason on Saturday against the Los Angeles Chargers in Santa Clara, they'll ...

The Chargers released their third and final unofficial depth chart ahead of the preseason game against the 49ers.

The 49ers' starting cornerback hurt his hamstring about four weeks ago and has not been practicing since. This has allowed the team to see Dallis Flowers and Darrell Luter under a microscope and may ...

The 49ers lost another player to season-ending injured reserve, as a running back has suffered a devastating injury.