The wreck occurred just before midnight Tuesday on Interstate 10 near Stockton Street.

Florida Highway Patrol said one of the men was ejected from a 2016 Lexus sedan during the crash.

Two men were killed in an overnight crash on Interstate 10 in Duval County, according to the Florida Highway Patrol.

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A 56-year-old Florida man was killed in Kimble County after the wreckage of a 12-vehicle crash on Interstate 10 Saturday night, according to the Texas Department of Public Safety.

The crash involved four tractor semi-trailers, a box truck, a Dodge van, an Audi passenger car and Toyota pickup truck.