The skin is the primary physical barrier against harmful substances in the environment. But there is a significant difference in the protective capacity of the skin across individuals. Knowing the ...

Scientists have used mathematical and computer modeling to demonstrate the impact of skin homeostasis on driver and passenger mutations. All normal human tissues acquire mutations over time. Some of ...

All normal human tissues acquire mutations over time. Some of these mutations may be driver mutations that promote the development of cancer through increased proliferation and survival, while other ...

Growing cells in the laboratory is an art that humans have mastered decades ago. Recreating entire three-dimensional tissues is much more challenging. Researchers are developing a new hydrogel-based ...

Researchers at the University of Iowa (UI) Health Care and colleagues at the Texas Biomedical Research Institute, and Boston University, used human skin explants to track the cellular route that the ...