There can be many reasons why the Mouse double-click does not open files & folders in Windows. Here are some fixes to resolve this issue.

Wearing out your mouse with all that double-clicking? Here's a secret: Windows can get by on single clicks--if you know where to tweak it.

Click on the Processes tab and you can see how much each application is using and then close as many programs and browser tabs as you can. Test your mouse to see if that solved the problem.

Need to make your mouse click automatically? You can automate mouse clicks using OP Auto Clicker for Windows 11/10. Learn how!