Opioid receptors are a subset of G protein–coupled receptors (GPCRs). These membrane proteins transmit signals into the cell ...

G-protein coupled receptors (GPCRs) are proteins triggered by ligands (protein-binding chemicals) from outside cells to ...

Mapping how Narcan reverses opioid overdose can provide a molecular blueprint for developing more effective drugs against overdose.

Researchers at USF Health are making dramatic strides in understanding how new opioid compounds work inside the body to ...

Anxiety-related disorders can have a profound impact on the mental health and quality of life of affected individuals. Understanding the neural circuits and molecular mechanisms that trigger anxiety ...

Researchers at Geneva University Hospital in Geneva, Switzerland, found that the use of alpha-2 agonists with opioids in surgical patients decreased post-surgical opioid use by 25 to 30 percent. The ...

WHO recently launched new guidance on Opioid agonist maintenance treatment as an essential health service: implementation ...

Opioid antagonists are medications people can take to treat opioid use disorder. They help by reducing withdrawal symptoms, addressing cravings, and managing overdoses. Doctors prescribe opioid ...