The Scientist2mon
A Deep Dive into Viral Vectors for Gene Therapy
Adeno-associated viral (AAV) vectors in particular have high transduction rates and reduced toxicity concerns compared to other viral vectors. However, these delivery vehicles present some application ...
Nature1y
Non-viral delivery promises a true alternative for cell therapy developers
One way to achieve non-viral transduction is by using electroporation to introduce single-strand (ssDNA) or double-strand DNA (dsDNA) into the cell. CAR T cells produced with such non-viral ...
Nature5d
The HIV Tat protein transduction domain improves the biodistribution of β-glucuronidase expressed from recombinant viral vectors
Recent studies showed that a peptide, the protein transduction domain (PTD ... when expressed from viral vectors. The Tat motif allowed for mannose-6-phosphate (M6P) independent uptake in vitro ...
Nanowerk8mon
Viral Vectors for Gene Delivery: Biotechnology Applications and Benefits
Viral vectors are engineered viruses that are used to deliver genetic material into cells for various applications, such as gene therapy, vaccine development, and biotechnology research. These viruses ...