As organisms develop from embryos, groups of cells migrate and reshape themselves to form all manner of complex tissues.

Drastic differences in the ways cells behave and respond to drugs are observed when cells are cultured using 3D instead of 2D approaches. These differences are driving the adoption of more advanced ...

An increasing amount of research indicates that more translational and appropriate observations can be made with organoids and micro-tissues in comparison with 2D monolayer cell models. This is most ...

Evaluating Anticancer Drugs and Building Tissue and Tumor Co-Culture Models Among Uses The need for new tools and technologies to decrease the cost of drug discovery and reduce animal testing has been ...

The utilization of multi-cell tumor spheroids as an oncology research model has quickly increased because of a greater understanding of the effects of the tumor microenvironment, along with the ...

In basic and applied biology research, such as investigations of stem cells and drug screening, spheroid cell cultures are valuable, providing a more realistic test environment than the 2D cultures ...

In research that could shed light on the growth and formation of complex tissue architectures, Brown University engineers ...

Isolation of spheroid-forming cells is important to investigate cancer stem cell (CSC) characteristics. However, conventional tumor spheroid culture methods have not proven suitable because the ...

Scientists use 3D cell culture models, including tumour spheroids and human organoids, to gain new knowledge about human diseases and develop novel therapeutics and treatment strategies. However, ...

Researchers have used the ALMA telescope and found old elliptical galaxies in the universe can form from intense star formation within early galaxy cores. An international team of researchers ...