THE importance of the sodium ion in edema is well recognized. If a specific method were available for producing selective inhibition of the renal tubular reabsorption of sodium from the glomerular ...

Extract: This report concerns two patients with primary renal tubular acidosis (RTA) in whom the abnormality in hydrogen excretion was shown to result from inappropriate urinary loss of bicarbonate ...

THE earliest lesions of certain types of experimental nephrocalcinosis involve the distal portions of the renal tubules and the collecting ducts. 1,2 Disturbances in renal tubular function might ...

A reduction in urinary citrate levels may be the mechanism underlying the higher incidence of kidney stones in patients taking PPIs, according to investigators. Individuals who use proton pump ...

Ammonia and Kidney Failure Study implicates an inability of a CKD patient's kidneys to excrete the daily acid load. Lower urinary ammonia excretion, a marker of an impaired ability of the kidneys to ...

Renal drug excretion involves filtration, reabsorption, and secretion, crucial for drug clearance and minimizing toxicity. The study models renal clearance using pharmacokinetic parameters, validated ...

SARS-CoV-2-associated acute kidney injury (AKI) is one of the more frequently encountered organ involvements in COVID-19 - in as many as 80% of critically ill patients, according to a recent study [2] ...