Nature

A two-stage joint model approach to handle incomplete time dependent markers in survival data through inverse probability weight and multiple imputation

Joint models for longitudinal and survival data are essential in biomedical research, enabling the simultaneous analysis of biomarker progression and clinical events. These models account for the ...
Nature

Modeling unobserved heterogeneity in multistate event history data using frailty and weighted survival approaches

Frailty models and multistate models (MSMs) are powerful tools used in survival analysis to handle heterogeneity among individuals and to better represent complex processes involving multiple ...
Business Wire

Ivonescimab Plus Chemotherapy Demonstrates Statistically Significant and Clinically Meaningful Improvement in Progression-Free Survival in Patients with EGFR-Mutant Non-Small ...

MIAMI--(BUSINESS WIRE)--Summit Therapeutics Inc. (NASDAQ: SMMT) (“Summit,” “we,” or the “Company”) today announced topline results from the Phase III clinical trial, HARMONi, the first global Phase ...
Cure Today

Imfinzi Combo Improves Progression Free Survival in Ovarian Cancer

The DUO-O trial showed significant improvement in progression-free survival with Imfinzi, Avastin, and Lynparza, but no significant overall survival benefit. The study was a double-blind, multicenter ...
Business Wire

Emerging Data for Lantern Pharma’s Investigational Drug LP-300 Demonstrates 8.3-Month Median Progression-Free Survival in Patients with EGFR L858R Lung Cancer After Targeted ...

Lantern Pharma Schedules Type C Meeting with the FDA to Advance HARMONIC™ Protocol Amendments Targeting This High-Need Population, Reflecting LP-300’s Novel Mechanism of Action and the Rapidly ...