The artist’s impression shows how the HIV capsid penetrates the jelly-like permeability barrier of a nuclear pore. To smuggle its genome through this defense line into the cell nucleus, it has evolved ...

In order for HIV to replicate, the viral genome must enter into the cell nucleus and integrate into the host cell chromosome. Previous work suggests that the entry proceeds through nuclear pore ...

Scientists from Duke-NUS Medical School (Duke-NUS) have derived a structural model of a transporter at the blood-brain barrier called Mfsd2a. This is the first molecular model of this critical ...

BioIVT, a leading provider of research models and services for drug development, today announced that it has acquired Santa Clara, CA-based Optivia Biotechnology and its comprehensive portfolio of ...

Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year. To replicate and spread the infection, the virus must smuggle its genetic material into the ...

Bile acids are essential for digestion, metabolism, and hormonal signaling. Their circulation between the liver and intestine, known as enterohepatic circulation, depends on a coordinated network of ...

Citrate is a metabolite essential to the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a central role in this process and has previously been linked to a ...