The Major Histocompatibility Complex is a genetic region characterized by a high density of genes, many of them involved in the immune response. Of considerable importance are the HLA class I and ...

Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from within the cell on ...

Decision support for treatment of patients with glioblastoma: A systems biology approach enabled by explainable AI.

Discover how dietary arginine regulates MHC class I translation to boost antitumor and antiviral defense. Read more on AMJ.

Researchers utilizes single-cell long-read sequencing to reveal thousands of previously invisible tumor-specific isoforms in ...

In the ever-evolving world of cell therapy, researchers often turn to T cells—a type of white blood cell—to transform the way we treat cancer. This is true for CAR T therapy, a modern cancer ...