Long-read RNA sequencing (RNA-seq) technologies have revolutionized transcriptomic research by enabling the sequencing of full-length RNA molecules, thus providing a more accurate characterization of ...

The low-pass whole genome sequencing technique involves sequencing each genome base several times. It is increasingly popular in agricultural studies, as agricultural genomes typically have a broader ...

Oxford Nanopore long-read sequencing helps researchers derive insights from difficult-to-read genomic sections and detect large structural variants. However, the technique uses high molecular weight ...

Advances in next-generation sequencing (NGS) have propelled genomics research to new heights. With the introduction of new sequencing platforms such as Element Biosciences’ AVITI and Ultima Genomics’ ...

Single cell whole genome amplification (WGA) enables single cell whole genome sequencing (scWGS), typically carried out using short reads at low coverage 1, which generally only detects Mb-scale CNVs, ...

16S metagenomic sequencing enables targeted exploration of microbial communities by combining amplification of the 16S ribosomal RNA (rRNA) gene, a reliable phylogenetic marker, with next generation ...

Short-read RNA-seq provides robust gene-level expression but is limited in resolving full-length transcripts and splice variants. Long-read sequencing addresses these limitations by capturing complete ...

Here, Aaron Wenger, Principal Scientist – Bioinformatics at PacBio (CA, USA), explores how advances in accuracy, throughput and cost are making long-read sequencing more accessible at scale. Advances ...

Long-read sequencing is transforming the landscape of genomic research, offering exceptional resolution and accuracy in the analysis of complex genetic structures. From research in genetic analysis to ...