The boxes along the top and right-hand side of the figure represent potential pathophysiological cellular and end-organ mechanisms that underlie the disability of peripheral arterial disease and ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Claudication is muscular pain, cramping, or fatigue that typically occurs during exercise and goes away with rest. Claudication is primarily a symptom of conditions that reduce blood flow in the legs, ...