A new research paper was published in Volume 16 of Genes & Cancer on January 20, 2025, entitled, "Analysis of pathogenic variants in retinoblastoma reveals a potential gain of function mutation." ...

SAN DIEGO--(BUSINESS WIRE)--n-Lorem, a nonprofit foundation, announced today the publication of an article in the journal Nucleic Acid Therapeutics that explores potential regulatory approaches that ...

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function ...

Chronic mucocutaneous candidiasis (CMC) is a condition characterised by recurrent or persistent infections of the skin, nails and mucous membranes caused predominantly by Candida species. A ...

Epidemiology and outcomes of disseminated intravascular coagulation in pancreatic cancer patients admitted with sepsis: Insights from a national database. This is an ASCO Meeting Abstract from the ...

SCLC has a poor prognosis with less than 7% 5-year survival, and limited surgical specimens hinder understanding. FAK inhibition is identified as a potential therapeutic target due to high-frequency ...

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

PROGRAMMING ALERT: Watch Dr. Siegel discuss this topic and more on "Fox & Friends" and "America's Newsroom" on Tuesday, May 6. Gain-of-function research has many purposes, including gauging the ...

Biosafety hawks were initially optimistic that the incoming second Trump administration would at last place binding constraints on so-called "dangerous gain-of-function" research, in which pathogens ...