Repair of DNA double-strand breaks via homologous recombination can produce double Holliday junctions (dHJs) that require enzymatic separation. Topoisomerase IIIα (TopIIIα) together with RMI1 ...
A type of filamentous protein assembly known as agglomerates appear to offer advantages in intracellular engineering and synthetic biology and little to no deleterious effects on cellular fitness, ...
Alzheimer's disease is one of the devastating illnesses mankind is facing in the 21 st century. The main pathogenic event in Alzheimer's disease is believed to be the aggregation of the β-amyloid (Aβ) ...