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Researchers decode tertiary structure of DNA aptamer–ATP complex and improve binding affinity
DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of ...
Explore cytosine, a fundamental base in DNA and RNA, its critical role in gene regulation and epigenetics, and its significance in biotechnology and genetic diseases.
The articles in this Subject space describe the science surrounding the structure and function of DNA. Here, you will find information on the chemical structure of DNA; organization of DNA into ...
Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to ...
The work underscores an essential principle in molecular biology: structure and function are deeply intertwined. By ...
Could DNA be glycosylated? A new study published in Engineering explores this intriguing question, suggesting that DNA might undergo glycosylation, a process that could revolutionize our understanding ...
In 1957, just four years after Francis Crick and other scientists solved the riddle of DNA’s structure—the now famous double ...
Scientists have constructed ''DNA droplets'' comprising designed DNA nanostructures. The droplets exhibit dynamic functions such as fusion, fission, Janus-shape formation, and protein capture ...
This is called the Wobble hypothesis. Until now such synonymous changes in DNA were deemed “silent” mutations that did not affect the structure or function of the resulting protein.
Sixty years after the discovery of DNA's spiraling, ladderlike structure first hinted at the mechanism by which life copies itself, one of the Nobel Prize medals honoring this achievement is up ...
A new research paper in the journal EMBO Reports describes how DNA damage can affect neural health and function.
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