Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...

Predicting protein–DNA binding specificity is a challenging yet essential task for understanding gene regulation. Protein–DNA complexes usually exhibit binding to a selected DNA target site, whereas a ...

How does your body produce millions of antibodies from one genome? New research reveals how two closely related proteins help ...

Nucleotide excision repair is a DNA repair pathway which detects and fixes various DNA lesions that distort the structure of DNA. In bacteria, the pathway starts with the UvrA protein which has two ...

Researchers from the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee, together with collaborators from ETH Zürich, the Malopolska Center of Biotechnology and the ...

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins - ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

Researchers have captured the first atomic-level views of human SMUG1, a key enzyme involved in repairing damaged DNA.

Researchers at Oregon Health & Science University have identified a previously unrecognised role for the cancer-associated ...