Nucleotide excision repair (NER) is a highly conserved pathway that recognises and removes bulky lesions and helix‐distorting adducts from DNA, thereby safeguarding genomic integrity. In bacteria, the ...

The chemical compound methyleugenol naturally occurs in culinary herbs such as basil and is ingested by humans through food. In the liver, the substance can be activated by enzymes and cause genetic ...

Methyleugenol is a component of essential oils and is found in basil, tarragon, nutmeg, and fennel. When ingested through ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

A new study suggests melatonin supplements may help night shift workers boost their body's DNA repair processes, potentially offsetting some of the damage linked to working overnight. The findings are ...

A new review highlights how human evolution has shaped the presence of pathogenic variations in DNA damage repair (DDR) genes, offering a new perspective on why modern populations face increased ...

Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists have analyzed the molecular evolution of tumors after exposure to mutagenic chemicals.

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...

A protein best known for driving cancer growth also helps damaged tumor cells survive by repairing their DNA, according to a new study that could influence how some cancers are treated. Researchers at ...

Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists from the German Cancer Research Center (DKFZ) and the Universities of Cambridge and ...