The Bowtie 2 software achieves fast, sensitive, accurate and memory-efficient gapped alignment of sequencing reads using the full-text minute index and hardware-accelerated dynamic programming ...

The Genomics & Bioinformatics shared resource helped the Hutch’s Henikoff Lab develop a better chromatin mapping technique.

While the normal practice is to use various alignment techniques like BLAST, CLUSTALW, etc. to measure such differences, our approach allows for a novel method of genome characterization called ...

Innovative laser alignment methods enable precise imaging of biomolecules, advancing single-particle diffraction techniques and structural analysis.

Bioinformatics workflows The declining cost and increasing accessibility of next-generation sequencing (NGS) have led to the permeation of these techniques throughout the life sciences. The sequencing ...