The field of viral pathogenesis research is rapidly uncovering the importance of host-cell lipid metabolism as a key determinant of viral replication and ...

An illustration shows a molecule nestled inside a large lumpy green mass. According to researchers' predictions, the antiviral candidate, venetoclax (red and purple), could limit SARS-CoV-2's ability ...

Pocapavir, the investigational antiviral drug studied, can allow susceptible polioviruses to sensitize resistant ones. Although this strategy seemed to work in previous lab culture studies of the ...

A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications. Now, a new ...

Viruses are masters of stealth. From the moment a virus enters the host's body, it begins hijacking its cells. First, the virus binds to a specific protein on the cell's surface through a lock-and-key ...

Many known viruses pose a continuing threat to public health, and we are constantly dealing with the possibility that new viruses could emerge to cause more health problems. We also seem to lack a ...

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus ...

Scientists have discovered a novel antiviral defense system in sea anemones, entirely distinct from human immunity. This ...

The arrival of Paxlovid in December 2021 marked another turning point in the COVID-19 pandemic—an effective antiviral that has since successfully treated millions. But like many antivirals before it, ...