The unwinding or 'unzipping' of duplex DNA to produce single-stranded DNA (ssDNA) is essential for all processes that involve a ssDNA template or reaction intermediate, including DNA replication, ...
Bipolar spindle assembly requires a balance of forces where kinesin-5 produces outward pushing forces to antagonize the inward pulling forces from kinesin-14 or dynein. Accordingly, Kinesin-5 ...
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