True crime. Real justice. To miss it would be a crime.

48 Hours investigates “The Rx Defense,” examining the Friendswood, Texas shooting where a teen blamed acne drug Accutane for killing one friend and seriously injuring another.

CBS’ official description for this new episode of 48 Hours reads like this, “On Dec. 23, 2023, police were called to a Texas ...

"48 Hours" airs Saturdays at 10/9c on CBS and streams on Paramount+. Our 38th season premiered on Saturday, Sept. 27, 2025.